BAIT
CEBPA
C/EBP-alpha, CEBP
CCAAT/enhancer binding protein (C/EBP), alpha
GO Process (5)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
CTPS1
CTPS, IMD24
CTP synthase 1
GO Process (8)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- B cell proliferation [IMP]
- CTP biosynthetic process [IDA, IMP]
- T cell proliferation [IMP]
- nucleobase-containing compound metabolic process [TAS]
- nucleobase-containing small molecule interconversion [TAS]
- nucleobase-containing small molecule metabolic process [TAS]
- response to drug [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- CTP synthase activity [EXP, IDA, IGI, IMP]
- CTP synthase activity [EXP, IDA, IGI, IMP]
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBP?.
C/EBP? represents a paradigm intrinsically disordered transcription factor containing short linear motifs and post-translational modifications (PTM). Unraveling C/EBP? protein interaction networks is a prerequisite for understanding the multi-modal functions of C/EBP? in hematopoiesis and leukemia. Here, we combined arrayed peptide matrix screening (PRISMA) with BioID to generate an in vivo validated and isoform specific interaction map of C/EBP?. The myeloid C/EBP? ... [more]
iScience Jun. 25, 2021; 24(6);102686 [Pubmed: 34189442]
Throughput
- High Throughput
Additional Notes
- Used arrayed peptide matrix screening (PRISMA) method
- significance threshold (FDR less than 0.1)
Curated By
- BioGRID