CEBPB
Gene Ontology Biological Process
- brown fat cell differentiation [ISO]
- cellular response to amino acid stimulus [ISO]
- embryonic placenta development [ISO]
- fat cell differentiation [ISO]
- mammary gland epithelial cell differentiation [ISO]
- mammary gland epithelial cell proliferation [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- neuron differentiation [ISO]
- positive regulation of fat cell differentiation [ISO, ISS]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of interleukin-6 biosynthetic process [ISO]
- regulation of transcription involved in cell fate commitment [ISO, ISS]
- regulation of transcription, DNA-templated [IC, ISO, ISS]
- response to endoplasmic reticulum stress [ISO, ISS]
- response to lipopolysaccharide [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO, ISS]
- chromatin binding [ISO]
- glucocorticoid receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- sequence-specific DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO, ISS]
- chromatin binding [ISO]
- glucocorticoid receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- sequence-specific DNA binding [IDA, ISO]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
NAP1L1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBP?.
CCAAT enhancer-binding protein beta (C/EBP?) is a pioneer transcription factor that specifies cell differentiation. C/EBP? is intrinsically unstructured, a molecular feature common to many proteins involved in signal processing and epigenetics. The structure of C/EBP? differs depending on alternative translation initiation and multiple post-translational modifications (PTM). Mutation of distinct PTM sites in C/EBP? alters protein interactions and cell differentiation, suggesting ... [more]
Throughput
- High Throughput
Additional Notes
- C/EBP beta core interactions
- PRISMA: Protein Interaction Screen on Peptide Matrix
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CEBPB NAP1L1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | High | - | BioGRID | 673578 |
Curated By
- BioGRID