BAIT
CEBPB
Il6dbp, NF-IL6, TCF5
CCAAT/enhancer binding protein (C/EBP), beta
GO Process (18)
GO Function (11)
GO Component (6)
Gene Ontology Biological Process
- brown fat cell differentiation [ISO]
- cellular response to amino acid stimulus [ISO]
- embryonic placenta development [ISO]
- fat cell differentiation [ISO]
- mammary gland epithelial cell differentiation [ISO]
- mammary gland epithelial cell proliferation [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- neuron differentiation [ISO]
- positive regulation of fat cell differentiation [ISO, ISS]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of interleukin-6 biosynthetic process [ISO]
- regulation of transcription involved in cell fate commitment [ISO, ISS]
- regulation of transcription, DNA-templated [IC, ISO, ISS]
- response to endoplasmic reticulum stress [ISO, ISS]
- response to lipopolysaccharide [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO, ISS]
- chromatin binding [ISO]
- glucocorticoid receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- sequence-specific DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO, ISS]
- chromatin binding [ISO]
- glucocorticoid receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- sequence-specific DNA binding [IDA, ISO]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CMSS1
C3orf26
cms1 ribosomal small subunit homolog (yeast)
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBP?.
CCAAT enhancer-binding protein beta (C/EBP?) is a pioneer transcription factor that specifies cell differentiation. C/EBP? is intrinsically unstructured, a molecular feature common to many proteins involved in signal processing and epigenetics. The structure of C/EBP? differs depending on alternative translation initiation and multiple post-translational modifications (PTM). Mutation of distinct PTM sites in C/EBP? alters protein interactions and cell differentiation, suggesting ... [more]
iScience Mar. 29, 2019; 13();351-370 [Pubmed: 30884312]
Throughput
- High Throughput
Additional Notes
- C/EBP beta core interactions
- PRISMA: Protein Interaction Screen on Peptide Matrix
Curated By
- BioGRID