BAIT
FRPR-8
CELE_F53A9.5, F53A9.5
FMRFamide Peptide Receptor family
GO Process (0)
GO Function (0)
GO Component (0)
Caenorhabditis elegans
PREY
FLP-7
CELE_F49E10.3, F49E10.3
flp-7 encodes an MVRFamide-containing peptide that, upon injection into A. suum, produces paralysis and loss of locomotory waveforms, increased body length, and decreased cAMP production.
GO Process (3)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Caenorhabditis elegans
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
System-wide mapping of peptide-GPCR interactions in C. elegans.
Neuropeptides and peptide hormones are ancient, widespread signaling molecules that underpin almost all brain functions. They constitute a broad ligand-receptor network, mainly by binding to G protein-coupled receptors (GPCRs). However, the organization of the peptidergic network and roles of many peptides remain elusive, as our insight into peptide-receptor interactions is limited and many peptide GPCRs are still orphan receptors. Here ... [more]
Cell Rep Sep. 26, 2023; 42(9);113058 [Pubmed: 37656621]
Throughput
- High Throughput
Additional Notes
- high throughput peptide-GPCR interaction screen
Curated By
- BioGRID