BAIT
EPB41L2
4.1-G, 4.1G, RP3-324N14.1
erythrocyte membrane protein band 4.1-like 2
GO Process (0)
GO Function (0)
GO Component (8)
Gene Ontology Cellular Component
Homo sapiens
PREY
PARP1
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1, RP11-125A15.2
poly (ADP-ribose) polymerase 1
GO Process (12)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- DNA repair [TAS]
- cellular response to insulin stimulus [IDA]
- double-strand break repair [IMP]
- gene expression [TAS]
- macrophage differentiation [TAS]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- protein ADP-ribosylation [IDA]
- protein poly-ADP-ribosylation [IDA]
- transcription from RNA polymerase II promoter [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
circEPB41L2 blocks the progression and metastasis in non-small cell lung cancer by promoting TRIP12-triggered PTBP1 ubiquitylation.
The metastasis of non-small cell lung cancer (NSCLC) is the leading death cause of NSCLC patients, which requires new biomarkers for precise diagnosis and treatment. Circular RNAs (circRNAs), the novel noncoding RNA, participate in the progression of various cancers as microRNA or protein sponges. We revealed the mechanism by which circEPB41L2 (hsa_circ_0077837) blocks the aerobic glycolysis, progression and metastasis of ... [more]
Cell Death Discov Feb. 10, 2024; 10(1);72 [Pubmed: 38341427]
Throughput
- Low Throughput
Additional Notes
- circEPB41L2 circular RNA
Curated By
- BioGRID