GABRG2
Gene Ontology Biological Process
- adult behavior [ISO]
- cellular response to histamine [ISO, ISS]
- chloride transmembrane transport [IDA, ISO]
- chloride transport [TAS]
- gamma-aminobutyric acid signaling pathway [ISO, TAS]
- ion transmembrane transport [TAS]
- post-embryonic development [ISO]
- signal transduction [ISO]
- synaptic transmission [ISO]
- synaptic transmission, GABAergic [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GABRA4
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
BDNF selectively regulates GABAA receptor transcription by activation of the JAK/STAT pathway.
The gamma-aminobutyric acid (GABA) type A receptor (GABA(A)R) is the major inhibitory neurotransmitter receptor in the brain. Its multiple subunits show regional, developmental, and disease-related plasticity of expression; however, the regulatory networks controlling GABA(A)R subunit expression remain poorly understood. We report that the seizure-induced decrease in GABA(A)R alpha1 subunit expression associated with epilepsy is mediated by the Janus kinase (JAK)/signal ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID