BAIT
MALAT1
HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO2853, mascRNA, PRO1073
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
KHSRP
FBP2, FUBP2, KSRP
KH-type splicing regulatory protein
GO Process (5)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
GATA4-activated lncRNA MALAT1 promotes osteogenic differentiation through inhibiting NEDD4-mediated RUNX1 degradation.
Postmenopausal osteoporosis (PMOP) brings a lot of inconvenience to patients and serious economic burden to society. The osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays vital role in the process of PMOP treatment. However, the functional mechanism remains unclear. In this study, GATA4, MALAT1 and KHSRP were downregulated in bone tissues of PMOP patients, while NEDD4 was overexpressed. ... [more]
Cell Death Discov May. 08, 2023; 9(1);150 [Pubmed: 37156809]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KHSRP MALAT1 | Affinity Capture-RNA Affinity Capture-RNA An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis. | Low | - | BioGRID | - |
Curated By
- BioGRID