BAIT
MEX3A
MEX-3A, RKHD4
mex-3 RNA binding family member A
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
LIF
CDF, DIA, HILDA, MLPLI
leukemia inhibitory factor
GO Process (17)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- leukemia inhibitory factor signaling pathway [IDA]
- multicellular organismal development [TAS]
- negative regulation of hormone secretion [IDA]
- positive regulation of MAPK cascade [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of histone H3-K27 acetylation [IDA]
- positive regulation of macrophage differentiation [IDA]
- positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [IDA]
- positive regulation of peptidyl-serine phosphorylation [IDA]
- positive regulation of peptidyl-serine phosphorylation of STAT protein [IDA]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of protein localization to nucleus [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of tyrosine phosphorylation of Stat1 protein [IDA]
- positive regulation of tyrosine phosphorylation of Stat3 protein [IDA]
- regulation of metanephric nephron tubule epithelial cell differentiation [IDA]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.
Breast cancer (BC) is the most frequent malignant tumor in women worldwide with exceptionally high morbidity. The RNA-binding protein MEX3A plays a crucial role in genesis and progression of multiple cancers. We attempted to explore its clinicopathological and functional significance in BC in which MEX3A is expressed.The expression of MEX3A detected by RT-qPCR and correlated the results with clinicopathological variables ... [more]
Breast Cancer Res Treat Oct. 01, 2023; 201(3);353-366 [Pubmed: 37433992]
Throughput
- High Throughput
Curated By
- BioGRID