PREY

TRIOBP

AI428493, EST478828, Tara, mKIAA1662, RP23-414K1.1
TRIO and F-actin binding protein
GO Process (1)
GO Function (2)
GO Component (3)
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice.

Nakaya N, Sultana A, Munasinghe J, Cheng A, Mattson MP, Tomarev SI

Olfactomedin 1 (Olfm1) is a secreted glycoprotein that is preferentially expressed in neuronal tissues. Here we show that deletion of exons 4 and 5 from the Olfm1 gene, which encodes a 52 amino acid long region in the N-terminal part of the protein, increased neonatal death and reduced body weight of surviving homozygous mice. Magnetic resonance imaging analyses revealed reduced ... [more]

Exp Neurol Dec. 01, 2013; 250();205-18 [Pubmed: 24095980]

Throughput

  • Low Throughput

Curated By

  • BioGRID