BAIT
PLN
CMD1P, CMH18, PLB, RP3-509L4.2
phospholamban
GO Process (19)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- blood circulation [NAS]
- cytosolic calcium ion homeostasis [IC]
- negative regulation of ATPase activity [IDA, ISS]
- negative regulation of calcium ion binding [IDA, ISS]
- negative regulation of calcium ion import [ISS]
- negative regulation of calcium ion import into sarcoplasmic reticulum [ISS]
- negative regulation of calcium ion transmembrane transporter activity [IDA, ISS]
- negative regulation of calcium ion transport [IDA]
- negative regulation of calcium-transporting ATPase activity [IDA]
- negative regulation of catalytic activity [ISS]
- negative regulation of heart rate [IMP]
- regulation of calcium ion transport [IDA, ISS]
- regulation of calcium-transporting ATPase activity [IDA]
- regulation of cardiac muscle cell contraction [IC]
- regulation of cardiac muscle cell membrane potential [IC]
- regulation of heart contraction [IMP]
- regulation of relaxation of cardiac muscle [IC]
- regulation of the force of heart contraction [IC]
- relaxation of cardiac muscle [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ELN
SVAS, WBS, WS
elastin
GO Process (6)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
SARS-CoV-2 envelope protein alters calcium signaling via SERCA interactions.
The clinical management of severe COVID-19 cases is not yet well resolved. Therefore, it is important to identify and characterize cell signaling pathways involved in virus pathogenesis that can be targeted therapeutically. Envelope (E) protein is a structural protein of the virus, which is known to be highly expressed in the infected host cell and is a key virulence factor; ... [more]
Sci Rep Sep. 11, 2024; 14(1);21200 [Pubmed: 39261533]
Throughput
- Low Throughput
Curated By
- BioGRID