BAIT
ORF10
SARS-CoV2 ORF10, SARS-CoV-2 ORF10, 10, A0A663DJA2_9BETC, GU280_gp11
ORF10 protein
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus 2
PREY
DHX9
DDX9, LKP, NDH2, NDHII, RHA
DEAH (Asp-Glu-Ala-His) box helicase 9
GO Process (10)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- ATP catabolic process [IBA, TAS]
- CRD-mediated mRNA stabilization [IMP]
- DNA duplex unwinding [TAS]
- RNA processing [IBA]
- RNA splicing [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- mRNA splicing, via spliceosome [TAS]
- osteoblast differentiation [IDA]
- positive regulation of type I interferon production [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.
A deep understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-host interactions is crucial to developing effective therapeutics and addressing the threat of emerging coronaviruses. The role of noncoding regions of viral RNA (ncrRNAs) has yet to be systematically scrutinized. We developed a method using MS2 affinity purification coupled with liquid chromatography-mass spectrometry and designed a diverse set of bait ... [more]
mSystems Aug. 31, 2023; 8(4);e0013523 [Pubmed: 37314180]
Throughput
- High Throughput
Additional Notes
- Protein RNA - MS was carried out to identify high confidence protein interactors for the SARS-CoV-2 ncrRNA NRC11 (ORF10)
Curated By
- BioGRID