BAIT

ORF10

SARS-CoV2 ORF10, SARS-CoV-2 ORF10, 10, A0A663DJA2_9BETC, GU280_gp11
ORF10 protein
COVID-19 Coronavirus Project
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus 2
PREY

MTHFSD

methenyltetrahydrofolate synthetase domain containing
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

Jiang L, Xiao M, Liao QQ, Zheng L, Li C, Liu Y, Yang B, Ren A, Jiang C, Feng XH

A deep understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-host interactions is crucial to developing effective therapeutics and addressing the threat of emerging coronaviruses. The role of noncoding regions of viral RNA (ncrRNAs) has yet to be systematically scrutinized. We developed a method using MS2 affinity purification coupled with liquid chromatography-mass spectrometry and designed a diverse set of bait ... [more]

mSystems Aug. 31, 2023; 8(4);e0013523 [Pubmed: 37314180]

Throughput

  • High Throughput

Additional Notes

  • Protein RNA - MS was carried out to identify high confidence protein interactors for the SARS-CoV-2 ncrRNA NRC11 (ORF10)

Curated By

  • BioGRID