BAIT
BSG
5F7, CD147, EMMPRIN, M6, OK, TCSF, UNQ6505/PRO21383
basigin (Ok blood group)
GO Process (9)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- cellular metabolic process [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- leukocyte migration [TAS]
- protein targeting to plasma membrane [ISS]
- pyruvate metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TMEM5
HP10481, MDDGA10
transmembrane protein 5
GO Process (1)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Extracellular proximal interaction profiling by cell surface-targeted TurboID reveals LDLR as a partner of liganded EGFR.
Plasma membrane proteins play pivotal roles in receiving and transducing signals from other cells and from the environment and are vital for cellular functionality. Enzyme-based, proximity-dependent approaches, such as biotin identification (BioID), combined with mass spectrometry have begun to illuminate the landscape of proximal protein interactions within intracellular compartments. To extend the potential of these approaches to study the extracellular ... [more]
Sci Signal Nov. 05, 2024; 17(861);eadl6164 [Pubmed: 39499777]
Throughput
- High Throughput
Additional Notes
- Extracellular TurboID (ecTurboID)
- High confidence interactions had a 1% BFDR and a minimum of two spectral counts.
Curated By
- BioGRID