BAIT

NFATC3

NFAT4, NFATX
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Homo sapiens
PREY

IGF2BP3

CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3
insulin-like growth factor 2 mRNA binding protein 3
Human Papilloma Virus (HPV) Project
Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

CircNFATC3 promotes the proliferation of gastric cancer through binding to IGF2BP3 and restricting its ubiquitination to enhance CCND1 mRNA stability.

Yang F, Ma Q, Huang B, Wang X, Pan X, Yu T, Ran L, Jiang S, Li H, Chen Y, Liu Y, Liang C, Ren J, Zhang Y, Wang S, Li W, Xiao B

Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) is an RNA binding protein with multiple roles in regulation of gene expression at the post-transcriptional level and is implicated in tumorigenesis and progression of numerous cancers including gastric cancer (GC). Circular RNAs (circRNAs) are a diverse endogenous noncoding RNA population that have important regulatory roles in cancer. However, circRNAs that ... [more]

J Transl Med Jun. 20, 2023; 21(1);402 [Pubmed: 37340423]

Throughput

  • Low Throughput

Additional Notes

  • Bait is circNFATC3

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
IGF2BP3 NFATC3
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Low/High-BioGRID
3754247

Curated By

  • BioGRID