BAIT
HNRNPD
Auf1, Hnrpd
heterogeneous nuclear ribonucleoprotein D
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
FKBP1B
12.6kDa, AW494148, FKBP12.6, calstabin2
FK506 binding protein 1b
GO Process (23)
GO Function (7)
GO Component (10)
Gene Ontology Biological Process
- T cell proliferation [IMP]
- chaperone-mediated protein folding [IBA]
- cytosolic calcium ion homeostasis [IMP, ISO]
- insulin secretion [IMP]
- negative regulation of heart rate [IMP]
- negative regulation of insulin secretion involved in cellular response to glucose stimulus [IMP]
- negative regulation of protein phosphatase type 2B activity [ISO]
- negative regulation of release of sequestered calcium ion into cytosol [IBA, ISO]
- negative regulation of ryanodine-sensitive calcium-release channel activity [ISO]
- neuronal action potential propagation [IMP]
- positive regulation of axon regeneration [ISO]
- positive regulation of cytosolic calcium ion concentration [IMP, ISO]
- positive regulation of sequestering of calcium ion [ISO]
- protein peptidyl-prolyl isomerization [IDA, ISO]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IMP]
- regulation of heart rate [IMP]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IMP, ISO]
- regulation of ryanodine-sensitive calcium-release channel activity [IMP]
- release of sequestered calcium ion into cytosol [IMP]
- release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IMP]
- response to glucose [IMP]
- response to redox state [ISO]
- smooth muscle contraction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each.
Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in mouse NIH/3T3 cells and RNA-protein complexes isolated using anti-myc tag antibody beads. Bound mRNAs were analyzed with Affymetrix microarrays. We have identified 508 potential target mRNAs ... [more]
PLoS ONE Nov. 13, 2018; 13(11);e0206823 [Pubmed: 30418981]
Throughput
- High Throughput
Curated By
- BioGRID