BAIT
HNRNPD
Auf1, Hnrpd
heterogeneous nuclear ribonucleoprotein D
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PSMD10
AW554874, RP23-149O3.6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
GO Process (12)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- cytoplasmic sequestering of NF-kappaB [ISO]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [ISO]
- negative regulation of MAPK cascade [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of release of cytochrome c from mitochondria [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity [ISO]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of protein ubiquitination [ISO]
- proteasome regulatory particle assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each.
Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in mouse NIH/3T3 cells and RNA-protein complexes isolated using anti-myc tag antibody beads. Bound mRNAs were analyzed with Affymetrix microarrays. We have identified 508 potential target mRNAs ... [more]
PLoS ONE Nov. 13, 2018; 13(11);e0206823 [Pubmed: 30418981]
Throughput
- High Throughput
Curated By
- BioGRID