BAIT
HNRNPD
Auf1, Hnrpd
heterogeneous nuclear ribonucleoprotein D
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CHP1
1500003O03Rik, AA960066, AI046351, Cahp, Chp, Sid470p, p24, vac, RP23-22A15.1
calcineurin-like EF hand protein 1
GO Process (23)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
- calcium ion-dependent exocytosis [ISO]
- cytoplasmic microtubule organization [ISO]
- membrane docking [ISO]
- membrane fusion [ISO]
- membrane organization [ISO]
- microtubule bundle formation [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of calcineurin-NFAT signaling cascade [ISO]
- negative regulation of phosphatase activity [ISO]
- negative regulation of protein autophosphorylation [ISO]
- negative regulation of protein import into nucleus [ISO]
- negative regulation of protein kinase activity [ISO]
- negative regulation of protein phosphorylation [ISO]
- negative regulation of protein ubiquitination [ISO]
- positive regulation of protein glycosylation [ISO]
- positive regulation of protein transport [ISO]
- positive regulation of sodium:proton antiporter activity [ISO]
- protein export from nucleus [ISO]
- protein oligomerization [ISO]
- protein stabilization [ISO]
- regulation of intracellular pH [ISO]
- regulation of neuron death [ISO]
- transcytosis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each.
Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in mouse NIH/3T3 cells and RNA-protein complexes isolated using anti-myc tag antibody beads. Bound mRNAs were analyzed with Affymetrix microarrays. We have identified 508 potential target mRNAs ... [more]
PLoS ONE Nov. 13, 2018; 13(11);e0206823 [Pubmed: 30418981]
Throughput
- High Throughput
Curated By
- BioGRID