BAIT

XPO7

EXP7, RANBP16

exportin 7

GO Process (1)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

protein export from nucleus [IDA]

Gene Ontology Molecular Function

nuclear export signal receptor activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

nuclear pore [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

PREY

AATF

BFR2, CHE-1, CHE1, DED, HSPC277

apoptosis antagonizing transcription factor

GO Process (8)

GO Function (4)

GO Component (5)

Gene Ontology Biological Process

apoptotic signaling pathway [TAS]

cellular response to DNA damage stimulus [IEP]

negative regulation of apoptotic process [IMP]

negative regulation of reactive oxygen species metabolic process [IDA]

negative regulation of superoxide anion generation [IDA]

neurotrophin TRK receptor signaling pathway [TAS]

positive regulation of apoptotic process [TAS]

positive regulation of transcription from RNA polymerase II promoter [IDA]

Gene Ontology Molecular Function

leucine zipper domain binding [IPI]
poly(A) RNA binding [IDA]
protein binding [IPI]
sequence-specific DNA binding transcription factor activity [IDA]

Gene Ontology Cellular Component

centrosome [IDA]

cytoplasm [IDA]

focal adhesion [IDA]

nucleolus [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

CRISPR-based screening identifies XPO7 as a positive regulator of senescence.

Li LZ, Yang K, Jing Y, Fan Y, Jiang X, Wang S, Liu GH, Qu J, Ma S, Zhang W

Protein Cell Aug. 01, 2023; 14(8);623-628 [Pubmed: 36897256]

Throughput

High Throughput

Curated By

BioGRID