BAIT
RNF10
RIE2
ring finger protein 10
GO Process (5)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
XRCC6
CTC75, CTCBF, G22P1, KU70, ML8, TLAA, CTA-216E10.7
X-ray repair complementing defective repair in Chinese hamster cells 6
GO Process (13)
GO Function (8)
GO Component (8)
Gene Ontology Biological Process
- DNA duplex unwinding [TAS]
- DNA ligation [TAS]
- DNA repair [TAS]
- double-strand break repair [TAS]
- double-strand break repair via nonhomologous end joining [IMP, TAS]
- establishment of integrated proviral latency [TAS]
- innate immune response [TAS]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of type I interferon production [TAS]
- telomere maintenance [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
CircRNF10 triggers a positive feedback loop to facilitate progression of glioblastoma via redeploying the ferroptosis defense in GSCs.
Glioma exhibit heterogeneous susceptibility for targeted ferroptosis. How circRNAs alterations in glioma promote iron metabolism and ferroptosis defense remains unclarified.The highly enriched circRNAs in glioblastoma (GBM) were obtained through analysis of sequencing datasets. Quantitative real-time PCR (qRT-PCR) was used to determine the expression of circRNF10 in glioma and normal brain tissue. Both gain-of-function and loss-of-function studies were used to assess ... [more]
J Exp Clin Cancer Res Sep. 19, 2023; 42(1);242 [Pubmed: 37723588]
Throughput
- High Throughput
Additional Notes
- Bait is circRNF10
Curated By
- BioGRID