BAIT
RNF10
RIE2
ring finger protein 10
GO Process (5)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PNPT1
COXPD13, DFNB70, OLD35, PNPASE, old-35
polyribonucleotide nucleotidyltransferase 1
GO Process (24)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- RNA catabolic process [IDA]
- RNA import into mitochondrion [IDA]
- RNA phosphodiester bond hydrolysis, exonucleolytic [IDA]
- RNA polyadenylation [IDA]
- cellular response to interferon-beta [IDA]
- cellular response to oxidative stress [IDA]
- mRNA catabolic process [IDA]
- mitochondrial RNA 3'-end processing [IMP]
- mitochondrial RNA 5'-end processing [IMP]
- mitochondrial RNA catabolic process [IDA]
- mitochondrial mRNA catabolic process [IDA]
- mitochondrial mRNA polyadenylation [IMP]
- mitochondrion morphogenesis [ISS]
- mitotic cell cycle arrest [IDA]
- negative regulation of growth [IDA]
- nuclear polyadenylation-dependent mRNA catabolic process [IDA]
- positive regulation of mRNA catabolic process [IMP]
- positive regulation of miRNA catabolic process [IDA]
- positive regulation of mitochondrial RNA catabolic process [IDA]
- protein homooligomerization [IDA]
- protein homotrimerization [IDA]
- rRNA import into mitochondrion [IDA]
- regulation of cellular respiration [ISS]
- regulation of cellular senescence [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
CircRNF10 triggers a positive feedback loop to facilitate progression of glioblastoma via redeploying the ferroptosis defense in GSCs.
Glioma exhibit heterogeneous susceptibility for targeted ferroptosis. How circRNAs alterations in glioma promote iron metabolism and ferroptosis defense remains unclarified.The highly enriched circRNAs in glioblastoma (GBM) were obtained through analysis of sequencing datasets. Quantitative real-time PCR (qRT-PCR) was used to determine the expression of circRNF10 in glioma and normal brain tissue. Both gain-of-function and loss-of-function studies were used to assess ... [more]
J Exp Clin Cancer Res Sep. 19, 2023; 42(1);242 [Pubmed: 37723588]
Throughput
- High Throughput
Additional Notes
- Bait is circRNF10
Curated By
- BioGRID