BAIT

E6

HpV16gp1
transforming protein
Human Papilloma Virus (HPV) Project
Synthetic Protein Interaction Project
GO Process (0)
GO Function (0)
GO Component (0)
Human papillomavirus (16)
PREY

GPATCH4

GPATC4, RP11-284F21.4
G patch domain containing 4
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Virus-Host Protein-Protein Interactions between Human Papillomavirus 16 E6 A1 and D2/D3 Sub-Lineages: Variances and Similarities.

Dayer G, Masoom ML, Togtema M, Zehbe I

High-risk strains of human papillomavirus are causative agents for cervical and other mucosal cancers, with type 16 being the most frequent. Compared to the European Prototype (EP; A1), the Asian-American (AA; D2/D3) sub-lineage seems to have increased abilities to promote carcinogenesis. Here, we studied protein-protein interactions (PPIs) between host proteins and sub-lineages of the key transforming E6 protein. We transduced ... [more]

Int J Mol Sci Oct. 27, 2020; 21(21); [Pubmed: 33121134]

Throughput

  • High Throughput

Additional Notes

  • HPV16 Asian-American (AA; D2/D3) sub-lineage
  • HPV16 European Prototype (EP; A1) sub-lineage

Curated By

  • BioGRID