BAIT

ALO1

D-arabinono-1,4-lactone oxidase, L000004264, YML086C
D-Arabinono-1,4-lactone oxidase; catalyzes the final step in biosynthesis of dehydro-D-arabinono-1,4-lactone, which is protective against oxidative stress
GO Process (2)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)
PREY

MMR1

YLR190W
Phosphorylated protein of the mitochondrial outer membrane; localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p
GO Process (1)
GO Function (0)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

A protein interaction map of the myosin Myo2 reveals a role for Alo1 in mitochondrial inheritance in yeast.

Chelius X, Rausch N, Bartosch V, Klecker M, Klecker T, Westermann B

Budding yeast cells multiply by asymmetric cell division. During this process, the cell organelles are transported by myosin motors along the actin cytoskeleton into the growing bud, and, at the same time, some organelles must be retained in the mother cell. The ordered partitioning of organelles depends on highly regulated binding of motor proteins to cargo membranes. To search for ... [more]

J Cell Sci Feb. 01, 2025; 138(3); [Pubmed: 39775849]

Throughput

  • Low Throughput

Ontology Terms

  • mitochondrial distribution (APO:0000297)

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
ALO1 MMR1
Negative Genetic
Negative Genetic

Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores.

High-0.1791BioGRID
2159101

Curated By

  • BioGRID