BAIT
HPO
CG11228, Dmel\CG11228, MST, MST2, dMST, hipo, Dmel_CG11228
hippo
GO Process (20)
GO Function (5)
GO Component (0)
Gene Ontology Biological Process
- R8 cell fate specification [IMP]
- apoptotic process [IMP]
- border follicle cell migration [IMP]
- cell proliferation [IMP]
- eye development [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IGI]
- morphogenesis of an epithelial sheet [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of glial cell proliferation [IMP]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of organ growth [TAS]
- negative regulation of transcription, DNA-templated [IDA]
- organ growth [IDA]
- positive regulation of apoptotic signaling pathway [IMP]
- protein phosphorylation [IDA, NAS]
- regulation of apoptotic signaling pathway [IMP]
- regulation of cell proliferation [IMP]
- response to ionizing radiation [IMP]
- retinal cell programmed cell death [IMP]
- stem cell proliferation [IDA]
Gene Ontology Molecular Function
Drosophila melanogaster
PREY
CG2678
B, Dmel\CG2678, anon-84Eb, Dmel_CG2678
CG2678 gene product from transcript CG2678-RB
GO Process (2)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID