BAIT

DYRK1A

DYRK, DYRK1, HP86, MNB, MNBH, MRD7
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
Alzheimer's Disease Project
Autism spectrum disorder (ASD) Project
Cell Cycle - Senescence Project
Human Papilloma Virus (HPV) Project
Parkinson's Disease Project
Homo sapiens
PREY

HNRNPH1

HNRPH, HNRPH1, hnRNPH
heterogeneous nuclear ribonucleoprotein H1 (H)
GO Process (5)
GO Function (4)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.

Pintacuda G, Hsu YH, Tsafou K, Li KW, Martin JM, Riseman J, Biagini JC, Ching JKT, Mena D, Gonzalez-Lozano MA, Egri SB, Jaffe J, Smit AB, Fornelos N, Eggan KC, Lage K

Autism spectrum disorders (ASDs) have been linked to genes with enriched expression in the brain, but it is unclear how these genes converge into cell-type-specific networks. We built a protein-protein interaction network for 13 ASD-associated genes in human excitatory neurons derived from induced pluripotent stem cells (iPSCs). The network contains newly reported interactions and is enriched for genetic and transcriptional ... [more]

Cell Genom Mar. 08, 2023; 3(3);100250 [Pubmed: 36950384]

Throughput

  • High Throughput

Additional Notes

  • log2 FC greater than 0 and FDR less than or equal to 0.1 as threshold for significant interactors

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
HNRNPH1 DYRK1A
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

High-BioGRID
2872349

Curated By

  • BioGRID