BAIT
TLK2
HsHPK, PKU-ALPHA
tousled-like kinase 2
GO Process (9)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IDA]
- cellular response to gamma radiation [IDA]
- chromosome segregation [IMP]
- intracellular signal transduction [IDA]
- negative regulation of autophagy [NAS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- peptidyl-serine phosphorylation [IDA]
- protein phosphorylation [IDA]
- regulation of chromatin assembly or disassembly [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KRT9
CK-9, EPPK, K9
keratin 9
GO Process (3)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
Autism spectrum disorders (ASDs) have been linked to genes with enriched expression in the brain, but it is unclear how these genes converge into cell-type-specific networks. We built a protein-protein interaction network for 13 ASD-associated genes in human excitatory neurons derived from induced pluripotent stem cells (iPSCs). The network contains newly reported interactions and is enriched for genetic and transcriptional ... [more]
Cell Genom Mar. 08, 2023; 3(3);100250 [Pubmed: 36950384]
Throughput
- High Throughput
Additional Notes
- log2 FC greater than 0 and FDR less than or equal to 0.1 as threshold for significant interactors
Curated By
- BioGRID