BAIT

E6

E6 protein, VE6_HPV18
Protein E6
Human Papilloma Virus (HPV) Project
GO Process (0)
GO Function (0)
GO Component (0)
Human papillomavirus (18)
PREY

TPI1

HEL-S-49, TIM, TPI, TPID
triosephosphate isomerase 1
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity.

White EA, Kramer RE, Tan MJ, Hayes SD, Harper JW, Howley PM

We have begun to define the human papillomavirus (HPV)-associated proteome for a subset of the more than 120 HPV types that have been identified to date. Our approach uses a mass spectrometry-based platform for the systematic identification of interactions between human papillomavirus and host cellular proteins, and here we report a proteomic analysis of the E6 proteins from 16 different ... [more]

J Virol Dec. 01, 2012; 86(24);13174-86 [Pubmed: 23015706]

Throughput

  • High Throughput

Ontology Terms

  • keratinocyte (CL:0000312)
  • skin (BTO:0001253)
  • keratinocyte cell line (BTO:0000375)

Curated By

  • BioGRID