BAIT

RNF181

HSPC238
ring finger protein 181
UPS Project
GO Process (1)
GO Function (1)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens
PREY

SFMBT2

RP11-393K12.3
Scm-like with four mbt domains 2
GO Process (1)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

circRNA-SFMBT2 orchestrates ER? activation to drive tamoxifen resistance in breast cancer cells.

Li Z, Li Y, Han D, Wang X, Li C, Chen T, Li W, Liang Y, Luo D, Chen B, Wang L, Zhao W, Yang Q

Dysregulated ER? signaling is responsible for endocrine resistance and eventual relapse in patients with estrogen receptor-positive (ER+) breast cancer. Thus, identifying novel ER? regulators is necessary to fully understand the mechanisms of endocrine resistance. Here, we identified circRNA-SFMBT2 to be highly expressed in ER+ breast cancer cells in comparison to ER- cells and found that high circRNA-SFMBT2 levels were related ... [more]

Cell Death Dis Jul. 31, 2023; 14(7);482 [Pubmed: 37524698]

Throughput

  • Low Throughput

Additional Notes

  • circRNA-SFMBT2

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
SFMBT2 RNF181
Protein-RNA
Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Low-BioGRID
3786308

Curated By

  • BioGRID