BAIT
SLC35F2
HSNOV1
solute carrier family 35, member F2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
HNRNPC
C1, C2, HNRNP, HNRPC, SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
GO Process (6)
GO Function (9)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- identical protein binding [IPI]
- mRNA 3'-UTR binding [IDA]
- nucleosomal DNA binding [IDA]
- poly(A) RNA binding [IDA]
- poly(U) RNA binding [IDA]
- protein binding [IPI]
- RNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- identical protein binding [IPI]
- mRNA 3'-UTR binding [IDA]
- nucleosomal DNA binding [IDA]
- poly(A) RNA binding [IDA]
- poly(U) RNA binding [IDA]
- protein binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
SLC35F2-SYVN1-TRIM59 axis critically regulates ferroptosis of pancreatic cancer cells by inhibiting endogenous p53.
Pancreatic cancer cells undergo intricate metabolic reprogramming to sustain their survival and proliferation. p53 exhibits a dual role in tumor cell ferroptosis. However, the precise role and mechanisms underlying wild-type p53 activation in promoting ferroptosis in pancreatic cancer cells remain obscure. In this study, we applied bioinformatics tools and performed an analysis of clinical tissue sample databases and observed a ... [more]
Oncogene Oct. 01, 2023; 42(44);3260-3273 [Pubmed: 37740007]
Throughput
- High Throughput
Curated By
- BioGRID