BAIT
ATG14
ATG14L, BARKOR, KIAA0831
autophagy related 14
GO Process (2)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ADRM1
ARM-1, ARM1, GP110
adhesion regulating molecule 1
GO Process (3)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy.
Autophagy is a fundamental biological process critical to all eukaryotic cellular life. Although autophagy has been increasingly studied, how its process is precisely coordinated remains an open question. ATG14 (ATG14L/Barkor) is known to play a crucial role in both autophagosome formation and autophagosome-lysosome fusion. However, how ATG14 is regulated, especially at the post-translation level, is still not clear. Here, we ... [more]
Cell Rep Sep. 26, 2023; 42(9);113045 [Pubmed: 37632749]
Throughput
- High Throughput
Curated By
- BioGRID