NDUFS1
Gene Ontology Biological Process
- ATP metabolic process [IMP]
- apoptotic mitochondrial changes [IDA]
- cellular metabolic process [TAS]
- cellular respiration [IMP]
- mitochondrial electron transport, NADH to ubiquinone [NAS]
- reactive oxygen species metabolic process [IMP]
- regulation of mitochondrial membrane potential [IMP]
- respiratory electron transport chain [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
NDUFS4
Gene Ontology Biological Process
- brain development [IMP]
- cAMP-mediated signaling [IMP]
- cellular metabolic process [TAS]
- cellular respiration [IMP]
- mitochondrial electron transport, NADH to ubiquinone [NAS]
- mitochondrial respiratory chain complex I assembly [IMP]
- positive regulation of fibroblast proliferation [IMP]
- reactive oxygen species metabolic process [IMP]
- regulation of protein phosphorylation [IMP]
- respiratory electron transport chain [TAS]
- response to cAMP [IMP]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
EndoMAP.v1 charts the structural landscape of human early endosome complexes.
Early or sorting endosomes are dynamic organelles that play key roles in proteome control by triaging plasma membrane proteins for either recycling or degradation in the lysosome1,2. These events are coordinated by numerous transiently associated regulatory complexes and integral membrane components that contribute to organelle identity during endosome maturation3. Although a subset of the several hundred protein components and cargoes ... [more]
Throughput
- High Throughput
Additional Notes
- Blue-native polyacrylamide gel co-fractionation-MS (BN-MS)
- High confidence protein interactions had a PCProphet score > 0.7 in at least two replicates.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NDUFS4 NDUFS1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
| NDUFS1 NDUFS4 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.4927 | BioGRID | 1265421 |
Curated By
- BioGRID