NSP13
CENPF
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- cell proliferation [NAS]
- chromosome segregation [IMP, NAS]
- kinetochore assembly [NAS]
- metaphase plate congression [IDA]
- mitotic cell cycle [IMP, TAS]
- mitotic spindle assembly checkpoint [NAS]
- negative regulation of transcription, DNA-templated [IDA]
- protein transport [IDA, IMP]
- regulation of G2/M transition of mitotic cell cycle [IMP]
- regulation of cell cycle [TAS]
- regulation of striated muscle tissue development [ISS]
- response to drug [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Human protein interaction networks of ancestral and variant SARS-CoV-2 in organ-specific cells and bodily fluids.
Understanding SARS-CoV-2 human protein-protein interactions (PPIs) and the host response to infection is essential for developing effective COVID-19 antivirals. However, how the ancestral virus and its variants remodel virus-host protein assemblies in various organ-specific cells and bodily fluids remains unclear. Here, we conduct 639 affinity-purifications by tagging and expressing 28 SARS-CoV-2 and spike proteins from the ancestral virus and four ... [more]
Throughput
- High Throughput
Additional Notes
- PPIs detected in saliva of COVID-19 patients infected with SARS-CoV-2 and its variants
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NSP13 CENPF | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3480298 | |
| NSP13 CENPF | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8738 | BioGRID | 2652435 | |
| NSP13 CENPF | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8738 | BioGRID | 2875384 | |
| NSP13 CENPF | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 1 | BioGRID | 3214737 |
Curated By
- BioGRID