SLC12A2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
DHCR24
Gene Ontology Biological Process
- apoptotic process [NAS]
- cell cycle arrest [NAS]
- cholesterol biosynthetic process [IMP, ISS, TAS]
- negative regulation of apoptotic process [IDA]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- oxidation-reduction process [IMP]
- regulation of neuron death [NAS]
- response to oxidative stress [IEP]
- skin development [ISS]
- small molecule metabolic process [TAS]
- tissue development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The solute carrier superfamily interactome.
Solute carrier (SLC) transporters form a protein superfamily that enables transmembrane transport of diverse substrates including nutrients, ions and drugs. There are about 450 different SLCs, residing in a variety of subcellular membranes. Loss-of-function of an unusually high proportion of SLC transporters is genetically associated with a plethora of human diseases, making SLCs a rapidly emerging but challenging drug target ... [more]
Quantitative Score
- 0.625104756 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- CompPASS and SAINTexpress scores were integrated with quantitative data using a multi-modal RBF classifier (Frommelt et al., Mol. Syst. Biol., 2025, PMID: 40355756).
- HEK 293 Jump-In cells
- PPI probability score = 0.625104756187809
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| DHCR24 SLC12A2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8382 | BioGRID | 3176877 |
Curated By
- BioGRID