BAIT

KR-H1

44/11, CG18783, CG45074, CG9167, Dmel\CG45074, Dmel_CG18783, Kr h, Kr-h, P381, Pow, l(2)05208, l(2)10642, Dmel_CG45074
Kruppel homolog 1
Drosophila melanogaster
PREY

ALPHATUB84B

1t, ALPHA 84C, BEST:LD32507, CG1913, DM1alpha, DTA1, Dmel\CG1913, T, TBA1_DROME, Talpha1, Tub, Tuba84B, Tubalpha1, a-tub84B, a1t, aTub84B, alpha-Tub, alpha-Tub84B, alpha-tubulin, alpha-tubulin 84B, alpha1, alpha1t, alpha1tub, alpha1tub84B, alpha84B, alphaT, alphaTUB, alphaTub1, alphaTub84, alphat-1, anon-EST:Liang-1.59, anon-EST:Liang-2.30, chr3R:2914276..2914416, clone 1.59, clone 2.30, l(3)84Bd, l(3)g3, ms(3)nc33, nc33, tubulin, Dmel_CG1913
alpha-Tubulin at 84B
Drosophila melanogaster

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

SUMOylation modulates the dual functions of Krueppel homolog 1 in transcriptional regulation of Broad-Complex expression.

He Q, Chen J, Chen S, Gao X

Insects undergo intricate metamorphosis processes governed by hormonal regulatory mechanisms, exemplified by the antagonistic actions of 20-hydroxyecdysone (20E) and juvenile hormone (JH). Krueppel homolog 1 (Kr-h1) is a key transcription factor mediating JH's antagonistic effects on 20E. Previous studies have shown that Kr-h1 plays dual roles in regulating the 20E signaling gene Broad-Complex (Br-C), repressing it in larvae and activating ... [more]

J Adv Res Jul. 22, 2025; (); [Pubmed: 40706986]

Throughput

  • High Throughput

Additional Notes

  • Affinity capture MS was carried out to identify high confidence protein interactors of SUMOylated Kr-h1 at white prepupae (WPP)

Curated By

  • BioGRID