BAIT
ACVR2B
ACTRIIB, ActR-IIB, HTX4
activin A receptor, type IIB
GO Process (15)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- BMP signaling pathway [IDA, IMP, TAS]
- activin receptor signaling pathway [TAS]
- anterior/posterior pattern specification [IMP]
- artery development [ISS]
- blood vessel remodeling [ISS]
- lymphangiogenesis [ISS]
- lymphatic endothelial cell differentiation [ISS]
- positive regulation of activin receptor signaling pathway [IDA]
- positive regulation of bone mineralization [IMP]
- positive regulation of osteoblast differentiation [IMP]
- regulation of transcription, DNA-templated [IDA]
- retina vasculature development in camera-type eye [ISS]
- signal transduction [IDA]
- transmembrane receptor protein serine/threonine kinase signaling pathway [TAS]
- venous blood vessel development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SNTB1
59-DAP, A1B, BSYN2, DAPA1B, SNT2, SNT2B1, TIP-43
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
GO Process (1)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions.
Protein-protein interactions organize the localization, clustering, signal transduction, and degradation of cellular proteins and are therefore implicated in numerous biological functions. These interactions are mediated by specialized domains able to bind to modified or unmodified peptides present in binding partners. Among the most broadly distributed protein interaction domains, PSD95-disc large-zonula occludens (PDZ) domains are usually able to bind carboxy-terminal sequences ... [more]
Mol Cell Proteomics Sep. 01, 2013; 12(9);2587-603 [Pubmed: 23722234]
Throughput
- High Throughput
Curated By
- BioGRID