TMEM43
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RTN4
Gene Ontology Biological Process
- apoptotic process [NAS]
- axonal fasciculation [IBA, ISS]
- cerebral cortex radial glia guided migration [ISS]
- endoplasmic reticulum tubular network organization [IMP]
- negative regulation of axon extension [IDA]
- negative regulation of axonogenesis [TAS]
- negative regulation of cell growth [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- regulation of apoptotic process [NAS]
- regulation of axonogenesis [TAS]
- regulation of branching morphogenesis of a nerve [ISS]
- regulation of cell migration [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interaction Proteomics of Polycystins 1 and 2 Reveal a Novel Role for the BLOC-1/BORC Lysosomal Positioning Complex.
PKD1 and PKD2 are the most commonly mutated genes in autosomal dominant polycystic kidney disease (ADPKD). However, the precise roles of the encoded polycystin 1/2 (PC1 and PC2) proteins, and how their functions are disrupted in ADPKD, remain unclear. Here, we characterize the protein interaction networks of PC1 and PC2 in cycling and ciliated cells using proximity-dependent biotinylation (BioID), identifying ... [more]
Throughput
- High Throughput
Additional Notes
- Proteins with p value less than 0.05 in T-test of the triple samples in wild-type TMEM43 and its S358L mutant cells
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RTN4 TMEM43 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9266 | BioGRID | 1190721 | |
| RTN4 TMEM43 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9108 | BioGRID | 2257578 | |
| RTN4 TMEM43 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9567 | BioGRID | 3189326 |
Curated By
- BioGRID