SUCLG2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GSTO1
Gene Ontology Biological Process
- L-ascorbic acid metabolic process [IDA]
- cellular response to arsenic-containing substance [IDA]
- glutathione derivative biosynthetic process [TAS]
- negative regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- positive regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [IC]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IC]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IDA]
- small molecule metabolic process [TAS]
- xenobiotic catabolic process [IDA]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Knockdown of SUCLG2 inhibits glioblastoma proliferation and promotes apoptosis through LMNA acetylation and the mediation of H4K16la lactylation.
Glioblastoma (GBM) is the most aggressive primary tumour in the central nervous system, and dynamic clonal evolution and interactions within the microenvironment cause its significant spatiotemporal heterogeneity. These interactions primarily manifest as metabolic reprogramming, mitochondrial dynamic imbalance, and epigenetic remodelling. SUCLG2 has been implicated in the progression of GBM; however, the underlying mechanism is unclear. This study aimed to investigate ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| GSTO1 SUCLG2 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 1.5971 | BioGRID | 2625792 |
Curated By
- BioGRID