BAIT

S

spike, SARS-CoV2 S, SARS-CoV2 spike, S protein, surface, SARS-CoV-2 spike, SARS-CoV-2 S, SPIKE_SARS2, PRO_0000449646, GU280_gp02
Spike glycoprotein; Surface glycoprotein
COVID-19 Coronavirus Project
Synthetic Protein Interaction Project
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus 2
PREY

CLGN

calmegin
GO Process (1)
GO Function (0)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

The comprehensive SARS-CoV-2 'hijackome' knowledge base.

Huuskonen S, Liu X, Poehner I, Redchuk T, Salokas K, Lundberg R, Maljanen S, Belik M, Reinholm A, Kolehmainen P, Tuhkala A, Tripathi G, Laine P, Belanov S, Auvinen P, Vartiainen M, Keskitalo S, Oesterlund P, Laine L, Poso A, Julkunen I, Kakkola L, Varjosalo M

The continuous evolution of SARS-CoV-2 has led to the emergence of several variants of concern (VOCs) that significantly affect global health. This study aims to investigate how these VOCs affect host cells at proteome level to better understand the mechanisms of disease. To achieve this, we first analyzed the (phospho)proteome changes of host cells infected with Alpha, Beta, Delta, and ... [more]

Cell Discov Dec. 09, 2024; 10(1);125 [Pubmed: 39653747]

Throughput

  • High Throughput

Additional Notes

  • SARS-CoV-2 (Omicron BA.1/5) strain S protein wildtype
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein A570D mutant (Alpha-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein A701V mutant (Beta-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein D138Y mutant (Gamma-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein D215G mutant (Beta-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein D614G mutant (Alpha, Beta, Gamma, Delta, BA.1, BA.5-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein D80A mutant (Beta-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein E484K mutant (Beta, Gamma-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein H655Y mutant (Gamma, BA.1, BA.5-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein L18F mutant (Gamma-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein L241-243del mutant (Beta-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein P26S mutant (Gamma-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein P681R mutant (Delta-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein Q52R mutant
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein R190S mutant (Gamma-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein S : L452R mutant (Delta, BA.5-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein T1027I mutant (Gamma-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein V1176F mutant (Gamma-strain associated mutation)
  • SARS-CoV-2 (Wuhan-Hu-1) strain S protein Y144del mutant (Alpha, BA.1-strain associated mutation)

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
S CLGN
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
3798912
S CLGN
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High1BioGRID
3210679
S CLGN
Co-fractionation
Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

High-BioGRID
3803756
S CLGN
Proximity Label-MS
Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

High208BioGRID
2806267

Curated By

  • BioGRID