NES
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [IDA]
- brain development [ISS]
- central nervous system development [NAS]
- embryonic camera-type eye development [ISS]
- negative regulation of catalytic activity [IDA]
- negative regulation of protein binding [IDA]
- positive regulation of intermediate filament depolymerization [ISS]
- positive regulation of neural precursor cell proliferation [ISS]
- stem cell proliferation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PRDX2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.
Nestin, a class IV intermediate filament protein, is generally considered as a putative marker of neural stem and progenitor cells in the central nervous system. Glioma is a common type of adult brain tumors, and glioblastoma (GBM) represents the most aggressive form of glioma. Here, we report that Nestin expression is significantly upregulated in human GBM, compared with other types ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NES PRDX2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 1447744 |
Curated By
- BioGRID