RAB1B
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
OCRL
Gene Ontology Biological Process
- cilium assembly [IMP]
- inositol phosphate metabolic process [TAS]
- lipid metabolic process [NAS]
- phosphatidylinositol biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- positive regulation of Rac GTPase activity [IDA]
- regulation of Rac GTPase activity [IDA]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking.
The small GTPase Rab1 is found in all eukaryotes and acts in both ER-to-Golgi transport and autophagy. Several Rab1 effectors and regulators have been identified, but the mechanisms by which Rab1 orchestrates these distinct processes remain incompletely understood. We apply MitoID, a proximity biotinylation approach, to expand the interactome of human Rab1A and Rab1B. We identify new interactors among known ... [more]
Throughput
- High Throughput
Additional Notes
- GTP-bound form (Q67L mutant)
- MitoID
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| OCRL RAB1B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 11.7382 | BioGRID | 2844886 |
Curated By
- BioGRID