PEX5
Gene Ontology Biological Process
- negative regulation of protein homotetramerization [IDA]
- protein import into peroxisome matrix [IGI, IMP, NAS]
- protein import into peroxisome matrix, docking [IDA]
- protein import into peroxisome matrix, translocation [IDA]
- protein import into peroxisome membrane [IMP]
- protein targeting to peroxisome [IDA, IMP]
- protein tetramerization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SCP2
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- bile acid biosynthetic process [TAS]
- bile acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- inositol trisphosphate biosynthetic process [IDA]
- lipid hydroperoxide transport [IDA]
- phospholipid transport [IDA]
- positive regulation of intracellular cholesterol transport [IDA, NAS]
- positive regulation of steroid metabolic process [IDA]
- progesterone biosynthetic process [IDA]
- protein localization to plasma membrane [IDA]
- small molecule metabolic process [TAS]
- steroid biosynthetic process [IDA]
- unsaturated fatty acid metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Peroxisomal interactome mapping enables network-based modelling of function and disease.
Peroxisomal dysfunction contributes to a broad spectrum of multisystem disorders, yet mechanistic understanding and therapeutic options remain limited, posing significant challenges for clinical management. Network-based computational strategies support hypothesis generation, biomarker discovery, and drug repurposing, but their usage is constrained by incomplete human interactome coverage-especially by scarcity of high-confidence protein-protein interaction (PPI) data for peroxisomal proteins. We present the first ... [more]
Throughput
- High Throughput
Additional Notes
- Bioluminescence resonance energy transfer (BRET)
Related interactions
Curated By
- BioGRID