BAIT

WTAP

Mum2, RP1-56L9.4
Wilms tumor 1 associated protein
GO Process (2)
GO Function (0)
GO Component (5)
Homo sapiens
PREY

CORO1C

HCRNN4
coronin, actin binding protein, 1C
GO Process (3)
GO Function (1)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

O-GlcNAcylation stabilized WTAP promotes GBM malignant progression in an N6-methyladenosine-dependent manner.

Qiu J, Zhao R, Ma C, Wang Q, Li B, Qi Y, Pan Z, Zhao S, Wang S, Gao Z, Guo X, Qiu W, Tang W, Guo X, Deng L, Xue H, Li G

Interactions between mesenchymal glioblastoma stem cells (MES GSCs) and myeloid-derived macrophages (MDMs) shape the tumor-immunosuppressive microenvironment (TIME), promoting the progression of glioblastoma (GBM). N6-methyladenosine (m6A) plays important roles in the tumor progression. However, the mechanism of m6A in shaping the TIME of GBM remains elusive.Single-cell RNA sequencing and bulk RNA-seq datasets were employed to identify the critical role of WTAP ... [more]

Neuro Oncol May. 15, 2025; 27(4);900-915 [Pubmed: 39671515]

Throughput

  • High Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
WTAP CORO1C
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
2566589

Curated By

  • BioGRID