TNKS
Gene Ontology Biological Process
- mitotic spindle organization [TAS]
- negative regulation of DNA binding [IDA]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of canonical Wnt signaling pathway [IMP]
- positive regulation of telomere maintenance via telomerase [IDA, IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein ADP-ribosylation [IDA]
- protein auto-ADP-ribosylation [IDA]
- protein localization to chromosome, telomeric region [IMP]
- protein poly-ADP-ribosylation [IDA]
- protein polyubiquitination [IDA]
- regulation of telomere maintenance via telomerase [IC]
- spindle assembly [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CACNA1S
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Comprehensive dataset of interactors for the entire PARP family using TurboID proximity labeling.
A comprehensive dataset detailing protein interactors for the PARP family has been generated using TurboID proximity labeling under standardized experimental conditions. V5-TurboID fusion constructs enabled identification of 6,314 high-confidence interacting proteins through mass spectrometry, capturing transient interactions undetectable by conventional methods. Parallel GFP-PARP localization experiments validated physiological subcellular distributions. The dataset reveals both shared and unique interactors across PARP members, ... [more]
Throughput
- High Throughput
Additional Notes
- Turbo ID
- log2FC greater than 1 and P less than 0.05
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TNKS CACNA1S | Protein-peptide Protein-peptide An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments. | High | - | BioGRID | - |
Curated By
- BioGRID