BAIT
USP50
ubiquitin specific peptidase 50
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
ACADM
ACAD1, MCAD, MCADH, RP4-682C21.1
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
GO Process (9)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- carnitine biosynthetic process [IMP]
- carnitine metabolic process, CoA-linked [IMP]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation [IMP, TAS]
- fatty acid beta-oxidation using acyl-CoA dehydrogenase [IDA, IMP]
- medium-chain fatty acid catabolic process [IDA]
- medium-chain fatty acid metabolic process [IDA]
- oxidation-reduction process [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Defining the human deubiquitinating enzyme interaction landscape.
Deubiquitinating enzymes (Dubs) function to remove covalently attached ubiquitin from proteins, thereby controlling substrate activity and/or abundance. For most Dubs, their functions, targets, and regulation are poorly understood. To systematically investigate Dub function, we initiated a global proteomic analysis of Dubs and their associated protein complexes. This was accomplished through the development of a software platform called CompPASS, which uses ... [more]
Cell Jul. 23, 2009; 138(2);389-403 [Pubmed: 19615732]
Quantitative Score
- 1.28 [Confidence Score]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007) [epithelial cell (BTO:0000414)]
Additional Notes
- exogenous expression of bait
Curated By
- BioGRID