BAIT
USP16
UBP-M, UBPM, MSTP039
ubiquitin specific peptidase 16
GO Process (13)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- cell cycle [TAS]
- cellular response to DNA damage stimulus [IDA]
- histone H2A K63-linked deubiquitination [IMP]
- histone deubiquitination [IDA]
- mitotic nuclear division [IDA]
- monoubiquitinated histone H2A deubiquitination [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription, DNA-templated [IMP]
- positive regulation of translational elongation [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein homotetramerization [IPI]
- regulation of proteasomal protein catabolic process [IBA]
- regulation of transcription from RNA polymerase II promoter [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
DBT
BCATE2, BCKAD-E2, BCKADE2, E2, E2B, RP11-305E17.3
dihydrolipoamide branched chain transacylase E2
GO Process (3)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Defining the human deubiquitinating enzyme interaction landscape.
Deubiquitinating enzymes (Dubs) function to remove covalently attached ubiquitin from proteins, thereby controlling substrate activity and/or abundance. For most Dubs, their functions, targets, and regulation are poorly understood. To systematically investigate Dub function, we initiated a global proteomic analysis of Dubs and their associated protein complexes. This was accomplished through the development of a software platform called CompPASS, which uses ... [more]
Cell Jul. 23, 2009; 138(2);389-403 [Pubmed: 19615732]
Quantitative Score
- 2.56 [Confidence Score]
Throughput
- High Throughput
Ontology Terms
- hek-293 cell (BTO:0000007) [epithelial cell (BTO:0000414)]
Additional Notes
- exogenous expression of bait
Curated By
- BioGRID