MUS7
Gene Ontology Biological Process
RAD52
Gene Ontology Biological Process
- DNA recombinase assembly [NAS]
- double-strand break repair via homologous recombination [IGI]
- gene conversion at mating-type locus, DNA repair synthesis [IMP]
- homologous recombination-dependent replication fork processing [IMP]
- mating type switching [IMP]
- meiotic DNA repair synthesis [IMP]
- mitotic recombination [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Growth Defect
A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.
Publication
The novel gene mus7(+) is involved in the repair of replication-associated DNA damage in fission yeast.
The progression of replication forks is often impeded by obstacles that cause them to stall or collapse, and appropriate responses to replication-associated DNA damage are important for genome integrity. Here we identified a new gene, mus7(+), that is involved in the repair of replication-associated DNA damage in the fission yeast Schizosaccharomyces pombe. The Deltamus7 mutant shows enhanced sensitivity to methyl ... [more]
Throughput
- Low Throughput
Ontology Terms
- vegetative growth (APO:0000106)
- resistance to chemicals (APO:0000087)
- radiation resistance (APO:0000084)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MUS7 RAD52 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 300527 |
Curated By
- BioGRID