Synthetic Growth Defect

A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.

Publication

Genetic interactions in the control of septation in Schizosaccharomyces pombe.

Marks J, Fankhauser C, Simanis V

We have used genetic and molecular techniques to investigate the interactions among genes required for the initiation and regulation of septum formation in Schizosaccharomyces pombe. Our data suggest that the products of the cdc7, cdc11, cdc14 and cdc16 genes interact. These activities may regulate the function of the cdc15 gene product. A model for the control of septation in fission ... [more]

J. Cell. Sci. Apr. 01, 1992; 101(0);801-8 [Pubmed: 1527180]

Throughput

  • Low Throughput

Ontology Terms

  • temperature sensitive growth (APO:0000092)
  • vegetative growth (APO:0000106)

Curated By

  • BioGRID