BAIT

IKBKG

AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
GO Process (32)
GO Function (8)
GO Component (8)

Gene Ontology Biological Process

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Expanding the substantial interactome of NEMO using protein microarrays.

Fenner BJ, Scannell M, Prehn JH

Signal transduction by the NF-kappaB pathway is a key regulator of a host of cellular responses to extracellular and intracellular messages. The NEMO adaptor protein lies at the top of this pathway and serves as a molecular conduit, connecting signals transmitted from upstream sensors to the downstream NF-kappaB transcription factor and subsequent gene activation. The position of NEMO within this ... [more]

PLoS ONE Jan. 26, 2010; 5(1);e8799 [Pubmed: 20098747]

Throughput

  • Low Throughput

Curated By

  • BioGRID