BAIT
DNT
CG17559, Dmel\CG17559, Dmel_CG17559
doughnut on 2
GO Process (7)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
TSC1
CG6147, Dmel\CG6147, TSC, dTSC, dTSC-1, dTSC1, rocky, Dmel_CG6147
CG6147 gene product from transcript CG6147-RA
GO Process (27)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- TORC1 signaling [IMP]
- cellular response to hypoxia [IMP]
- determination of adult lifespan [IMP]
- enteroendocrine cell differentiation [IMP]
- insulin receptor signaling pathway [NAS]
- intestinal stem cell homeostasis [IMP]
- larval midgut histolysis [IGI]
- lipid metabolic process [IGI]
- negative regulation of cell growth [IGI, IMP, TAS]
- negative regulation of cell proliferation [IGI, IMP]
- negative regulation of cell size [IGI, IMP, NAS, TAS]
- negative regulation of developmental growth [IMP]
- negative regulation of insulin receptor signaling pathway [IGI]
- negative regulation of organ growth [IGI, IMP]
- oogenesis [IGI]
- positive regulation of Ras GTPase activity [IDA]
- positive regulation of autophagy [IMP]
- regulation of cell cycle [IMP, TAS]
- regulation of cell growth [TAS]
- regulation of cell proliferation [IMP]
- regulation of organ growth [NAS]
- regulation of phosphorylation [IDA]
- regulation of reactive oxygen species metabolic process [IMP]
- regulation of timing of cell differentiation [IMP]
- response to nutrient [IMP]
- signal transduction [IGI]
- trachea morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID