BAIT
TSG101
TSG10, VPS23
tumor susceptibility 101
GO Process (11)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- endosomal transport [TAS]
- intracellular transport of virus [TAS]
- membrane organization [TAS]
- positive regulation of exosomal secretion [IMP]
- regulation of extracellular vesicular exosome assembly [IMP]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IC, IDA, IMP]
- viral budding [IMP, ISS]
- viral life cycle [TAS]
- viral process [TAS]
- viral protein processing [TAS]
- virion assembly [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RNF111
ARK
ring finger protein 111
GO Process (6)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- gene expression [TAS]
- positive regulation of transcription from RNA polymerase II promoter [TAS]
- positive regulation of transcription, DNA-templated [IMP]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.
In eukaryotic cells the stability and function of many proteins are regulated by the addition of ubiquitin or ubiquitin-like peptides. This process is dependent upon the sequential action of an E1-activating enzyme, an E2-conjugating enzyme, and an E3 ligase. Different combinations of these proteins confer substrate specificity and the form of protein modification. However, combinatorial preferences within ubiquitination networks remain ... [more]
Genome Res. Oct. 01, 2009; 19(10);1905-11 [Pubmed: 19549727]
Quantitative Score
- 4.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID