TSG101
Gene Ontology Biological Process
- endosome transport via multivesicular body sorting pathway [IC]
- epithelium development [IMP]
- germarium-derived female germ-line cyst formation [IMP]
- maintenance of apical/basal cell polarity [IMP]
- multivesicular body assembly [IMP]
- negative regulation of growth [IMP]
- negative regulation of growth of symbiont in host [IMP]
- negative regulation of imaginal disc growth [IMP]
- regulation of JAK-STAT cascade [IMP]
- terminal branching, open tracheal system [IMP]
- trachea morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
VPS37B
Gene Ontology Biological Process
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interaction mapping: a Drosophila case study.
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila melanogaster, most of them orthologous to human cancer-related and/or signaling proteins, against high-complexity fly cDNA libraries. More than 2300 protein-protein interactions (PPI) were identified, of ... [more]
Throughput
- High Throughput
Additional Notes
- Predicted Biological Score:A
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
TSG101 VPS37B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
VPS37B TSG101 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID